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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR1D1
All Species:
8.48
Human Site:
T246
Identified Species:
16.97
UniProt:
P20393
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20393
NP_068370.1
614
66805
T246
T
S
P
T
Q
H
P
T
P
G
P
M
G
P
S
Chimpanzee
Pan troglodytes
XP_516330
579
64584
E225
Q
T
A
L
P
A
Q
E
Q
L
R
P
K
P
Q
Rhesus Macaque
Macaca mulatta
O18924
505
57572
Y151
D
K
A
S
G
F
H
Y
G
V
H
A
C
E
G
Dog
Lupus familis
XP_542763
576
64407
L220
E
H
H
E
Q
T
A
L
P
A
Q
E
Q
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV55
615
66784
T247
T
S
P
T
P
H
P
T
S
G
S
M
G
P
S
Rat
Rattus norvegicus
Q63503
615
66675
T247
T
S
P
A
P
H
P
T
S
G
S
V
G
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509051
657
72899
E288
D
A
L
V
E
H
H
E
Q
A
T
L
T
A
Q
Chicken
Gallus gallus
O42101
501
57084
R147
Q
Q
K
K
A
L
I
R
A
N
G
L
K
L
E
Frog
Xenopus laevis
P37234
477
54037
F123
C
G
D
K
A
S
G
F
H
Y
G
V
H
A
C
Zebra Danio
Brachydanio rerio
NP_991292
637
69439
P272
V
G
P
Q
P
Q
P
P
A
V
P
V
A
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17671
1199
128515
T575
R
T
L
S
T
L
H
T
E
K
L
V
V
F
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUK7
514
56114
R160
A
E
D
C
L
I
L
R
N
N
R
N
R
C
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.1
22.7
50.3
N.A.
95.6
94.8
N.A.
45.5
21
25.4
58.8
N.A.
20.6
N.A.
25.5
N.A.
Protein Similarity:
100
63
39.9
63.1
N.A.
97
96.7
N.A.
58.9
33
40.3
67.9
N.A.
31.1
N.A.
41.2
N.A.
P-Site Identity:
100
6.6
0
13.3
N.A.
80
66.6
N.A.
6.6
0
0
26.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
13.3
6.6
13.3
N.A.
80
73.3
N.A.
26.6
6.6
6.6
33.3
N.A.
26.6
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
9
17
9
9
0
17
17
0
9
9
17
0
% A
% Cys:
9
0
0
9
0
0
0
0
0
0
0
0
9
9
9
% C
% Asp:
17
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
0
9
9
0
0
17
9
0
0
9
0
9
9
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
0
0
0
9
0
% F
% Gly:
0
17
0
0
9
0
9
0
9
25
17
0
25
0
9
% G
% His:
0
9
9
0
0
34
25
0
9
0
9
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
17
0
0
0
0
0
9
0
0
17
0
0
% K
% Leu:
0
0
17
9
9
17
9
9
0
9
9
17
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
17
0
9
0
0
0
% N
% Pro:
0
0
34
0
34
0
34
9
17
0
17
9
0
34
0
% P
% Gln:
17
9
0
9
17
9
9
0
17
0
9
0
9
9
25
% Q
% Arg:
9
0
0
0
0
0
0
17
0
0
17
0
9
0
17
% R
% Ser:
0
25
0
17
0
9
0
0
17
0
17
0
0
0
34
% S
% Thr:
25
17
0
17
9
9
0
34
0
0
9
0
9
0
0
% T
% Val:
9
0
0
9
0
0
0
0
0
17
0
34
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _